ArticleEndocrine2026
Clinical characteristics of 28 cases of primary adrenal lymphoma.
Article in Endocrine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to systematically characterize clinical manifestations, diagnostic findings (including imaging, endocrine laboratory evaluation, and histopathology), and clinical outcomes among patients with primary adrenal lymphoma (PAL), to refine diagnostic strategies and clinical management for this rare endocrine neoplasm.
methodsThis retrospective cohort study recruited 28 patients diagnosed with primary adrenal diffuse large B-cell lymphoma (DLBCL) at the First Affiliated Hospital of Zhengzhou University between April 2013 and December 2024. All baseline characteristics were systematically analyzed.
resultsTwenty-eight patients were enrolled in this cohort, with a median age of 62 years; 18 patients (64%) were male. Clinical manifestations were heterogeneous, with weight loss being the most common symptom, followed by lumbar or abdominal pain and anorexia. Bilateral adrenal masses were detected in 18 of the 28 participants, and tumor diameter exceeded 4 cm in 21 cases. Morning serum adrenocorticotropin (ACTH) and cortisol concentrations were measured in 19 patients. Seven individuals displayed normal ACTH and cortisol profiles, while 6 presented with early primary adrenal insufficiency (PAI). All 28 subjects underwent adrenal pathological testing, confirming DLBCL as the definitive histological subtype. Twenty-five patients received chemotherapy.
conclusionsIn conclusion, PAL predominantly affects elderly male patients, who often present with bilateral adrenal masses, weight loss, and early PAI. Our cohort demonstrates substantial interindividual heterogeneity in endocrine phenotypes. High clinical suspicion and prompt adrenal biopsy are therefore vital to facilitate early intervention and optimize patient outcomes.
Indexed as
Identifiers
42842154What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.