ArticleSleep & breathing = Schlaf & Atmung2026
Impact of CPAP therapy on geriatric depression scale scores in elderly patients with obstructive sleep apnea.
Article in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study is to investigate the effect of CPAP treatment on depression scores in OSA, which is associated with impaired quality of life and functional decline in the geriatric population.
methodsThe study was an ambispective cohort involving geriatric patients aged 65-80 with moderate-to-severe OSA confirmed by polysomnography. Initial depressive symptoms were assessed using the Geriatric Depression Scale (GDS). Participants were categorized based on their adherence to CPAP. Objective CPAP usage data, including mean nightly usage time and the percentage of nights used, were obtained from device downloads. Baseline predictors of depression were examined using multiple linear regression. The effect of CPAP adherence on post-treatment GDS scores was analyzed with analysis of covariance (ANCOVA), adjusting for initial depression scores. The model was also run with body mass index, lowest oxygen saturation and follow-up duration as additional covariates, and effect sizes were calculated.
resultsOf the 53 patients, 31 (58.5%) adhered to CPAP. Demographic and clinical characteristics were similar between adherent and non-adherent groups. Regression analysis showed that lower nocturnal oxygen saturation (p = 0.012) and higher body mass index (BMI) (p = 0.011) were independently associated with higher initial GDS scores, while the apnea-hypopnea index was not significantly related to depressive symptoms. After adjusting for initial GDS scores, the adherent group had significantly lower post-treatment depression scores compared to non-adherents (adjusted mean GDS: 7.15 ± 0.18 vs. 10.10 ± 0.21, p < 0.001). The adjusted mean difference was 2.95 points (95% CI 2.40-3.50; partial η² = 0.70). Mean nightly use was 6.44 ± 0.97 h in the adherent group and 2.41 ± 0.95 h in the non-adherent group, on 88.4 ± 15.0% and 36.0 ± 25.0% of nights respectively (p < 0.001).
conclusionsCPAP adherence was associated with a significant reduction in depressive symptoms in older adults with OSA. Nocturnal hypoxemia and obesity were key predictors of depression severity. These findings suggest that effective OSA treatment may improve mental health outcomes in the elderly.
Indexed as
Identifiers
42842090What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.