ArticleFish physiology and biochemistry2026
The impact of adding aloin to water on the stress resistance of goldfish under transportation stress.
Article in Fish physiology and biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transportation stress response can reduce the antioxidant and immune capabilities of fish. To develop a green and safe natural anti-stress agent, this study focused on goldfish (Carassius auratus) to investigate the alleviating effects and mechanisms of aloin against transportation stress. The effects of aloin (0, 50, 200 mg/L) on stress, antioxidant, and immune indicators under simulated transportation for 6 and 24 h were determined, and the expression of antioxidant, inflammatory, and complement-related genes was measured by qPCR. The results showed that transportation increased the serum glucose level, elevated tissue antioxidant enzyme activity, enhanced oxidative damage, and decreased tissue immune enzyme activity in goldfish. Aloin reduced stress response indicators, enhanced antioxidant activity and immune function, and reduced the total number of bacteria in the water body, with 200 mg/L being optimal. qPCR revealed that aloin improved goldfish's ability to cope with transportation stress by regulating the Nrf2-Keap1 antioxidant pathway in a tissue-specific manner, restoring the balance of pro-inflammatory and anti-inflammatory factors, activating the lectin complement pathway, and synergistically alleviating transportation stress in goldfish. In summary, aloin can alleviate transportation stress in goldfish, providing a practical basis for developing green anti-stress agents.
Indexed as
Identifiers
42842027What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.