Evidence map›Paper›PMID 42841927›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2026

Influence of left ventricular ejection fraction on the clinical outcome of percutaneous coronary interventions in heart transplant patients.

Luisa Elbinger, Tobias Schupp, Michael Behnes, Ibrahim Akin, Angelika Costard-Jäckle, Rene Schramm, Tanja Rudolph, Volker Rudolph, Mohamed Ayoub

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Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Luisa ElbingerDepartment of General and Interventional Cardiology/Angiology, Ruhr University Bochum, Heart and Diabetes Center NRW, Georgstr. 11, 32545, Bad Oeynhausen, Germany.
Tobias SchuppDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany.
Michael BehnesDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany.
Ibrahim AkinDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany.
Angelika Costard-JäckleDepartment of Thoracic and Cardiovascular Surgery, Ruhr University Bochum, Heart and Diabetes Center NRW, Georgstr. 11, 32545, Bad Oeynhausen, Germany.
Rene SchrammDepartment of Thoracic and Cardiovascular Surgery, Ruhr University Bochum, Heart and Diabetes Center NRW, Georgstr. 11, 32545, Bad Oeynhausen, Germany.
Tanja RudolphDepartment of General and Interventional Cardiology/Angiology, Ruhr University Bochum, Heart and Diabetes Center NRW, Georgstr. 11, 32545, Bad Oeynhausen, Germany.
Volker RudolphDepartment of General and Interventional Cardiology/Angiology, Ruhr University Bochum, Heart and Diabetes Center NRW, Georgstr. 11, 32545, Bad Oeynhausen, Germany.
Mohamed AyoubDepartment of General and Interventional Cardiology/Angiology, Ruhr University Bochum, Heart and Diabetes Center NRW, Georgstr. 11, 32545, Bad Oeynhausen, Germany. mayoub@hdz-nrw.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough cardiac allograft vasculopathy (CAV) represents a common complication in heart transplantation (HTX) recipients, data investigating predictors of prognosis in patients with CAV are limited. The study sought to investigate the prognostic impact of left ventricular ejection fraction (LVEF) undergoing percutaneous coronary intervention (PCI) in HTX recipients.

methodsPatients with HTX who underwent PCI between January 2011 and June 2023 were included retrospectively at one center. Baseline characteristics, as well as lesion and interventional characteristics were compared between patients with LVEF > 50% and ≤ 50%, further risk stratification was performed comparing patients with LVEF ≥ 50, 41-49 and ≤ 40% and LVEF as continuous variable (per % increase). The primary endpoint was all-cause mortality at 3 years, the key secondary endpoint was major adverse cardiac and cerebrovascular events (MACCE).

resultsOne hundred fifty-nine HTX recipients undergoing PCI were included with a median LVEF of 55% (i.e., LVEF > 50%: 67%; LVEF ≤ 50%: 33%). Patients with a reduced LVEF were younger (mean 54.1 vs. 59.3 years, p = 0.045), had a higher body mass index (mean 28.1 vs. 26.2 kg/m

conclusionIn patients undergoing PCI after HTX, a reduced LVEF was an independent predictor of lower technical and procedural success, and was independently associated with impaired long-term prognosis.

Indexed as

Cardiac allograft vasculopathyCoronary artery diseaseEjection fractionHeart transplantationHTXPercutaneous coronary interventions

Identifiers

PMID42841927

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.