Evidence map›Paper›PMID 42841902›Full record

ArticleUlusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES2026

Cumulative soft-sign burden is associated with clinically significant injury in hemodynamically stable penetrating neck trauma.

Hamdi Haluk Cali, Muzaffer Akkoca, Sibel Alicura Tokgoz, Ilker Sirin, Ozlem Akkoca, Furkan Yılmaz, Ayse Hicret Cali, Ismail Borazan

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Article in Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Hamdi Haluk CaliDepartment of Emergency Medicine, Ministry of Health Ankara Etlik City Hospital, Ankara-Türkiye.
Muzaffer AkkocaDepartment of General Surgery, Ministry of Health Ankara Etlik City Hospital, Ankara-Türkiye.
Sibel Alicura TokgozDepartment of Otolaryngology, Ministry of Health Ankara Etlik City Hospital, Ankara-Türkiye.
Ilker SirinDepartment of Emergency Medicine, Ministry of Health Ankara Etlik City Hospital, Ankara-Türkiye.
Ozlem AkkocaDepartment of Otolaryngology, Ministry of Health Ankara Bilkent City Hospital, Ankara-Türkiye.
Furkan YılmazDepartment of Emergency Medicine, Ministry of Health Ankara Bilkent City Hospital, Ankara-Türkiye.
Ayse Hicret CaliDepartment of Emergency Medicine, Ministry of Health Ankara Gülhane Training And Research Hospital, Ankara-Türkiye.
Ismail BorazanDepartment of Emergency Medicine, Ministry of Health Ankara Etlik City Hospital, Ankara-Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRisk stratification remains challenging in hemodynamically stable patients with penetrating neck trauma and no hard signs. We evaluated the association between cumulative soft-sign burden and clinically significant injury (CSI) requiring therapeutic intervention.

methodsThis retrospective cohort study included adults with penetrating neck trauma who were hemodynamically stable, had no hard signs, and underwent cervical computed tomography angiography (CTA). CSI was defined as a vascular or aerodigestive injury requiring therapeutic surgical or endovascular intervention. Soft-sign count was assessed using receiver operating characteristic analysis and logistic regression.

resultsOf 109 patients, 33 (30.3%) had CSI. The median soft-sign count was higher among patients undergoing therapeutic surgery (2 vs. 1; p<0.001). Soft-sign count showed good discrimination for CSI (AUC, 0.81; 95% CI, 0.71-0.90). A threshold of ≥1 soft sign yielded 93.9% sensitivity and a 91.7% negative predictive value, whereas ≥2 soft signs yielded 89.5% specificity and a 73.3% positive predictive value. Each additional soft sign was independently associated with higher odds of CSI (adjusted OR, 4.83; 95% CI, 2.42-9.64; p<0.001). Gunshot mechanism was also strongly associated with CSI (OR, 10.58; 95% CI, 2.68-41.75).

conclusionIncreasing soft-sign burden was strongly associated with CSI. The absence of soft signs reduced but did not eliminate the risk, whereas multiple soft signs identified a higher-risk group. Soft-sign count may support imaging prioritization and early surgical consultation but should not replace CTA.

Indexed as

Neck InjuriesWounds, PenetratingAdultComputed Tomography AngiographyFemaleHumansMaleMiddle AgedRetrospective Studies

Identifiers

PMID42841902
PMCPMC13678151

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