ArticleEmerging microbes & infections2026
Unravelling the transmission dynamics and evolutionary trajectory of mpox in South Korea: 2022-2025 outbreak.
Article in Emerging microbes & infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The 2022 monkeypox (mpox) outbreak, driven by clade IIb monkeypox virus (MPXV), was facilitated by human-to-human transmission, particularly within heavy-tailed sexual networks. APOBEC3-associated mutations have been a prominent feature of MPXV genomic evolution during the global outbreak. National genomic data were collected from clinical samples by the Korea Disease Control and Prevention Agency to examine the transmission dynamics and molecular evolution of MPXV. Target enrichment-based next-generation sequencing was used to generate high-quality genomes. Mutation profiling was used to identify key genetic changes; clustering based on common variants provided insights into national transmission dynamics and molecular evolution. Analysis of mpox-positive samples revealed the linkage of most cases to sub-lineage C.1 and a few cases to C.1.1. Genomic clustering revealed an uneven distribution of cases, with a dominant cluster accounting for a substantial proportion of domestic transmission while most other cluster remained relatively limited in size, consistent with heterogeneous transmission patterns. APOBEC3-associated mutations progressively accumulated during the outbreak and were frequently observed in genomic regions associated with viral structural integrity and cell-to-cell transmission and host-modulation, indicating continued genomic diversification during human-to-human transmission. Together with the dominance of localized clusters, these findings suggest heterogeneous transmission patterns and the possible contribution of epidemiologically unrecognized transmission to the spread of MPXV in South Korea. These results underscore value of integrating genomic surveillance and targeted interventions to characterize transmission patterns and monitor viral genomic changes of potential biological or public health relevance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.