ArticleClinical ophthalmology (Auckland, N.Z.)2026
Caregiver-Reported Stressors Involved in Caring for a Child with Optic Nerve Hypoplasia.
Article in Clinical ophthalmology (Auckland, N.Z.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: To characterize quality of life (QoL) and depressive symptoms among caregivers of children with optic nerve hypoplasia (ONH), identify associated demographic and clinical factors, and explore the measurement properties of a modified caregiver QoL instrument. Patients and Methods: This cross-sectional survey included 20 primary caregivers of children with ONH who completed a modified 20-item Caregiver's Congenital Glaucoma Quality of Life (CarCGQoL) questionnaire (0-40; higher scores indicate better self-reported QoL), the Patient Health Questionnaire-9 (PHQ-9; 0-27), and a demographic and clinical survey. CarCGQoL analyses required completion of ≥16 of 20 items; clinical and demographic associations and measurement properties were explored. Results: Caregivers had a mean age of 42.7±11.7 years, and 75% were mothers. In primary CarCGQoL analyses (n=19), scores were strongly inversely associated with PHQ-9 scores ( Conclusion: Depressive symptoms were common and closely associated with lower modified CarCGQoL scores, while bilateral ONH and nystagmus were associated with poorer caregiver-reported outcomes. These findings support greater attention to caregiver well-being in ONH care and further evaluation of the modified CarCGQoL in larger cohorts.
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