Evidence map›Paper›PMID 42840968›Full record

Trial reportFrontiers in neurology2026

Effects of acute sleep deprivation on individuals across different

He-Jin Wang, Ling-Ling Liu, Yi-Hang Li, Yu-Hui Qiu, Xue Xia, Ye-Feng Cai, Shi-Jie Zhang

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07085754 (Effects of Acute Sleep Deprivation on Individuals With Different APOE Genotypes), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07085754 narecruitingnot on this map

Effects of Acute Sleep Deprivation on Individuals With Different APOE Genotypes

TypeinterventionalSponsorYuhui QiuRan2025 to 2026Enrolled60ConditionsSleep, Sleep DeprivationArmsSleep Deprivation
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

He-Jin Wang *Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Ling-Ling Liu *Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Yi-Hang LiDepartment of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Yu-Hui QiuDepartment of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Xue XiaDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Ye-Feng CaiDepartment of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Shi-Jie ZhangDepartment of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sleep is crucial for the clearance of metabolic waste products. Sleep deprivation leads to the accumulation of amyloid- Methods: This prospective, randomized open-label, blinded-endpoint trial plans to enroll 60 healthy young adults. Participants will be stratified by Discussion: This study serves as the first randomized controlled trial (RCT) to explore the potential influence of acute sleep deprivation on plasma AD biomarkers across different Study protocol registration: ClinicalTrials.gov, identifier NCT07085754.

Indexed as

Apolipoproteins ESleep DeprivationAmyloid beta-PeptidesBiomarkersGenotypeHumansMalePeptide FragmentsProspective Studiestau ProteinsAmyloid beta-PeptidesApolipoproteins EBiomarkersPeptide Fragmentstau ProteinsAlzheimer’s diseaseAPOEbiomarkersmulti-omicssleep deprivation

Identifiers

PMID42840968
PMCPMC13640143

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.