ArticleThoracic research and practice2026
Small Airway Dysfunction in Asthma: Associations with Control and Quality of Life.
Article in Thoracic research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Clinical Assessment and Outcomes Across Respiratory Diseases.Thoracic research and practice · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSmall airway dysfunction (SAD) is an important but frequently underrecognized component of asthma. This study aimed to determine the prevalence of SAD in asthma, as assessed by impulse oscillometry (IOS), and to evaluate its association with clinical outcomes. MATERIAL AND
methodsThis cross-sectional study, with a 12-month prospective follow-up, included adult patients with asthma. SAD was defined by IOS as R5-R20 ≥0.07 kPa·s·L-
resultsSAD was identified in 63 of 98 participants (64.3%). SAD prevalence differed significantly across the five Global Initiative for Asthma treatment steps (
conclusionSAD is common among patients with asthma and is associated with poorer asthma control, lower quality of life, and an increased exacerbation burden. Higher R5-R20 remained associated with poorer quality of life after adjustment for spirometry, whereas its association with asthma control was attenuated and became non-significant after adjustment for forced expiratory volume in the first second. These findings support further evaluation of IOS-defined SAD as a potentially clinically relevant trait in asthma.
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