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Outcomes of Modified Sistrunk Procedure for Pediatric Thyroglossal Duct Cyst Removal: Systematic Review and Meta-Analysis.
Review in OTO open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This meta-analysis aims to evaluate the safety and efficacy of the modified Sistrunk procedure in pediatric patients with thyroglossal duct cyst. Data Sources: A comprehensive literature search was conducted across Ovid MEDLINE, Embase, CINAHL and The Cochrane Library, from inception to April 16, 2025. Review Methods: Screening and selection followed PRISMA guidelines, and the review protocol was prospectively registered with PROSPERO (CRD420251022683). Eligible studies included pediatric patients undergoing the modified Sistrunk procedure for thyroglossal duct cysts. Data extraction was performed independently by reviewers, and study quality was assessed using standardized appraisal tools. Pooled estimates for recurrence, complications, infection, postoperative drainage and operative time were calculated using a random-effects meta-analysis model to account for between-study variability. Results: Of 999 studies screened, 5 studies met the eligibility criteria, with a total of 937 pediatric patients with thyroglossal duct cyst undergoing modified Sistrunk procedure. The pooled recurrence rate was 4% (95% CI: 0.02, 0.07; Conclusions: The modified Sistrunk procedure appears to be a safe approach for the management of thyroglossal duct cysts for pediatric patients. However, heterogeneity in technique highlights the need for standardized definitions and high-quality studies to inform clinical guideline development.
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