Evidence map›Paper›PMID 42840647›Full record

ArticleClinical case reports2026

Refractory Pericardial Effusion Secondary to Central Hypothyroidism due to Empty Sella Syndrome: A Rare Case Report.

Bishal Mandal, Prativa Subedi, Bishal Kumar Yadav, Bipin Pandey, Bishwa Raj Adhikari, Saurav Jha, Milan Gaihre

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bishal MandalMaharajgunj Medical Campus, Institute of Medicine Maharajgunj Nepal.
Prativa SubediSUNY Upstate Medical University Syracuse New York USA.ORCID https://orcid.org/0000-0001-9134-579X
Bishal Kumar YadavMaharajgunj Medical Campus, Institute of Medicine Maharajgunj Nepal.
Bipin PandeyKathmandu University School of Medical Sciences Dhulikhel Kavre Nepal.
Bishwa Raj AdhikariMaharajgunj Medical Campus, Institute of Medicine Maharajgunj Nepal.
Saurav JhaManipal College of Medical Sciences Pokhara Nepal.ORCID https://orcid.org/0000-0001-7967-0039
Milan GaihreMaharajgunj Medical Campus, Institute of Medicine Maharajgunj Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Refractory pericardial effusion with a low free T4 but inappropriately normal TSH should prompt evaluation for central hypothyroidism, including pituitary MRI to identify treatable causes such as empty sella syndrome. Glucocorticoid cover must precede levothyroxine to prevent adrenal crisis in patients with possible hypopituitarism.

Indexed as

central hypothyroidismempty sella syndromelevothyroxinepericardial effusion

Identifiers

PMID42840647
PMCPMC13639525

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.