Evidence map›Paper›PMID 42840602›Full record

ArticleSmart molecules : open access2026

A dual-channel fluorescent probe for in situ imaging of mitochondrial superoxide and microenvironmental changes in Cd-induced hepatorenal dysfunction.

Zibo Zhai, Liang Tao, Jia Huang, Xijian Wang, Hailin Zhang, Yuandi Wang, Jiaoli Zhang, Dan Cheng, Longwei He, Songjiao Li

Abstract read
In one paragraph

Article in Smart molecules : open access, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zibo ZhaiSchool of Pharmaceutical Science Hengyang Medical School University of South China Hengyang China.
Liang TaoSchool of Pharmaceutical Science Hengyang Medical School University of South China Hengyang China.ORCID https://orcid.org/0009-0004-8479-2611
Jia HuangDepartment of Ultrasound Medicine The First Affiliated Hospital Hengyang Medical School University of South China Hengyang China.
Xijian WangSchool of Pharmaceutical Science Hengyang Medical School University of South China Hengyang China.
Hailin ZhangSchool of Pharmaceutical Science Hengyang Medical School University of South China Hengyang China.
Yuandi WangSchool of Pharmaceutical Science Hengyang Medical School University of South China Hengyang China.ORCID https://orcid.org/0000-0002-9056-906X
Jiaoli ZhangDepartment of Ultrasound Medicine The First Affiliated Hospital Hengyang Medical School University of South China Hengyang China.
Dan ChengSchool of Pharmaceutical Science Hengyang Medical School University of South China Hengyang China.ORCID https://orcid.org/0000-0002-3288-1426
Longwei HeSchool of Pharmaceutical Science Hengyang Medical School University of South China Hengyang China.ORCID https://orcid.org/0000-0002-8206-8783
Songjiao LiSchool of Pharmaceutical Science Hengyang Medical School University of South China Hengyang China.ORCID https://orcid.org/0009-0009-2289-9284

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium (Cd) is an environmental pollutant with high bioaccumulation and multi-organ toxicity, posing a major threat to human health, especially to the liver and kidneys. Fluorescent probes have shown great potential for disease-related imaging because of their high sensitivity and specificity. However, most existing probes cannot simultaneously image the liver and kidneys in vivo, which limits their application in hepatorenal disease studies. Increasing evidence suggests that ferroptosis, accompanied by mitochondrial dysfunction and oxidative stress, is involved in Cd-induced hepatorenal injury. Nevertheless, the dynamic changes in key mitochondrial parameters, including reactive oxygen species, polarity, and viscosity, remain poorly understood. Herein, we developed

Indexed as

cadmiumdual‐channel fluorescent probeferroptosishepatorenal injurysuperoxideviscosity/polarity

Identifiers

PMID42840602
PMCPMC13639408

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.