Evidence map›Paper›PMID 42840580›Full record

ReviewFrontiers in cell and developmental biology2026

Cystatin F as a neuroimmune effector in CNS inflammation and neurodegeneration.

Kaitlin Murray, Kellie Fernandez, Thomas E Lane

Abstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kaitlin MurrayDepartment of Neurobiology and Behavior, School of Biological Sciences, University of California, Irvine, CA, United States.
Kellie FernandezDepartment of Molecular Biology and Biochemistry, School of Biological Sciences, University of California, Irvine, CA, United States.
Thomas E LaneDepartment of Neurobiology and Behavior, School of Biological Sciences, University of California, Irvine, CA, United States.

Funding

Defining mechanisms of disease and repair in a viral model of multiple sclerosisR35NS116835 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Thomas E Lane · 2020 to 2026
$5.0M
Cystatin F expression on microglia is critical for constraining demyelination following viral infection of the central nervous systemF32AI194808 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI Kaitlin Murray · 2025 to 2026
$152k
NIAID NIH HHS F32 AI194808NINDS NIH HHS R35 NS116835
6 · The paper itself

Abstract

Cystatin F (

Indexed as

cystatin Finflammationneurodegenerationneuroimmunologyprotease inhibitor

Identifiers

PMID42840580
PMCPMC13639425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.