Evidence map›Paper›PMID 42840456›Full record

ArticleMedComm2026

Profiling Gut Microbiome and Metabolites Aids Diagnosis and Prediction of Progression in Mild Cognitive Impairment.

Birong Zhang, Richard Brown, Antony Bayer, Joanna Waring, B Paul Morgan, Julian R Marchesi, You Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedComm, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Birong ZhangDivision of Infection and Immunity School of Medicine Cardiff University Cardiff Wales UK.
Richard BrownDivision of Infection and Immunity School of Medicine Cardiff University Cardiff Wales UK.
Antony BayerUK Dementia Research Institute Cardiff School of Medicine Cardiff University Cardiff Wales UK.
Joanna WaringMemory Team Cardiff and Vale University Health Board Routledge Academic Centre University Hospital Llandough Penarth UK.
B Paul MorganDivision of Infection and Immunity School of Medicine Cardiff University Cardiff Wales UK.
Julian R MarchesiDivision of Digestive Diseases Department of Metabolism Digestion and Reproduction Faculty of Medicine Imperial College London London UK.
You ZhouDivision of Infection and Immunity School of Medicine Cardiff University Cardiff Wales UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence suggests a link between the gut microbiota and metabolome and mild cognitive impairment (MCI); however, it remains largely unknown whether these parameters can aid MCI diagnosis and predict disease progression. We comprehensively characterized gut microbiota and metabolomic profiles in fecal samples from 35 individuals, including 16 spousal pairs in which one partner had MCI. Compared with controls, MCI cases exhibited significantly elevated levels of

Identifiers

PMID42840456
PMCPMC13639709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.