Evidence map›Paper›PMID 42840447›Full record

ReviewFrontiers in medical technology2026

From sepsis biomarker discovery to regulated

Erika P Plata-Menchaca, Enrique Hernández-Jiménez

Abstract readReview
In one paragraph

Review in Frontiers in medical technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Erika P Plata-MenchacaMedicine Department, Universitat Autònoma de Barcelona, Barcelona, Spain.
Enrique Hernández-JiménezLoop Diagnostics S.L., StartUB!-University of Barcelona, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis remains a diagnostic challenge because early clinical manifestations are non-specific and microbiological confirmation often arrives too late to guide first-hour decisions. The 2026 Surviving Sepsis Campaign guidelines reinforce early clinical recognition using validated clinical scores, appropriate diagnostic strategies, and responsible antimicrobial use and de-escalation. Yet, initial management still frequently occurs under diagnostic uncertainty. Hundreds of biomarkers have been proposed to improve sepsis diagnosis, risk stratification and treatment guidance; however, only a limited subset has progressed from discovery to regulated

Indexed as

antimicrobial stewardshipbiomarkersendotoxin tolerancehost responsein vitro diagnosticsnear-patient testingsepsis—diagnostics

Identifiers

PMID42840447
PMCPMC13639665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.