Evidence map›Paper›PMID 42840293›Full record

ArticleBiochemistry and biophysics reports2026

Sleep restriction induces histoarchitectural and cellular remodeling in the rat distal colon: a peripheral consequence of circadian disruption.

Adriano Araujo Ferreira, Maria Jose Pastre, Aline Rosa Trevizan, Lainy Leiny de Lima, Amanda Gubert Alves Dos Santos, Gessilda Alcantara Nogueira-Melo, Gláucia Eloisa Munhoz de Lion Siervo, Glaura Scantamburlo Alves Fernandes, Marcelo Biondaro Gois, Débora de Mello Gonçales Sant'Ana

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Adriano Araujo FerreiraBiosciences and Pathophysiology Postgraduate Program - PBF/UEM, State University of Maringá, Avenue Colombo, 5790, CEP, Maringá, 87020-900, Brazil.
Maria Jose PastreBiosciences and Pathophysiology Postgraduate Program - PBF/UEM, State University of Maringá, Avenue Colombo, 5790, CEP, Maringá, 87020-900, Brazil.
Aline Rosa TrevizanBiosciences and Pathophysiology Postgraduate Program - PBF/UEM, State University of Maringá, Avenue Colombo, 5790, CEP, Maringá, 87020-900, Brazil.
Lainy Leiny de LimaComparative Biology Postgraduate Program - PGB/UEM, State University of Maringá, Avenue Colombo, 5790, CEP, Maringá, 87020-900, Brazil.
Amanda Gubert Alves Dos SantosBiosciences and Pathophysiology Postgraduate Program - PBF/UEM, State University of Maringá, Avenue Colombo, 5790, CEP, Maringá, 87020-900, Brazil.
Gessilda Alcantara Nogueira-MeloBiosciences and Pathophysiology Postgraduate Program - PBF/UEM, State University of Maringá, Avenue Colombo, 5790, CEP, Maringá, 87020-900, Brazil.
Gláucia Eloisa Munhoz de Lion SiervoDepartment of General Biology, Biological Sciences Center, State University of Londrina - UEL, Rodovia Celso Garcia Cid, PR 445 - Km 380, Campus Universita'rio, Londrina, 86057-970, Brazil.
Glaura Scantamburlo Alves FernandesDepartment of General Biology, Biological Sciences Center, State University of Londrina - UEL, Rodovia Celso Garcia Cid, PR 445 - Km 380, Campus Universita'rio, Londrina, 86057-970, Brazil.
Marcelo Biondaro GoisFaculty of Health Sciences, Federal University of Rondonópolis - PPGBIOS/FCS/UFR, Avenue dos Estudantes, 5055 - Cidade Universitária, Rondonópolis, MT, 78736-900, Brazil.
Débora de Mello Gonçales Sant'AnaBiosciences and Pathophysiology Postgraduate Program - PBF/UEM, State University of Maringá, Avenue Colombo, 5790, CEP, Maringá, 87020-900, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep restriction disrupts circadian organization and represents a behavioral condition with systemic consequences that extend beyond the central nervous system. In this study, we evaluated structural and cellular changes in the distal colon of rats exposed to sustained sleep restriction. Sixteen male

Indexed as

Circadian disruptionGoblet cellsMast cellsMyenteric plexusNeuro-glial remodelingSubmucosal plexus

Identifiers

PMID42840293
PMCPMC13638796

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.