Evidence map›Paper›PMID 42840282›Full record

ArticleBiophysics and physicobiology2026

Mechanical self-organization of the actin cytoskeleton in artificial cells.

Makito Miyazaki

Abstract read
In one paragraph

Article in Biophysics and physicobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Makito MiyazakiRIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The actin cytoskeleton generates diverse cellular functions, including intracellular positioning, symmetry breaking, and cell migration, through dynamic self-organization. Despite extensive molecular characterization of actin-binding proteins, the physical principles by which local molecular interactions give rise to cell-scale organization remain incompletely understood. Artificial cells provide a powerful platform for addressing this question because they enable precise control over molecular composition, geometry, and physical boundary conditions while minimizing the complexity inherent to living cells. In this review, we describe how artificial cell systems have been used to investigate the emergence of actin-dependent intracellular organization and motility. Using the cytoplasmic extracts of

Indexed as

cell migrationintracellular positioningsymmetry breakingsynthetic biologyXenopus laevis

Identifiers

PMID42840282
PMCPMC13639344

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.