Evidence map›Paper›PMID 42840097›Full record

ArticleFrontiers in microbiology2026

High-throughput sequencing reveals the virome characteristics of wastewater in Gansu Province, China from 2024 to 2026.

Yabei Xu, Xiaohong Zhao, Shang Gao, Jinbo Xiao, Qian Yang, Jingjing Xu, Yuecong Xie, Yixin Xu, Xinghao Ye, Tianjiao Ji and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yabei XuNational Laboratory for Poliomyelitis, WHO WPRO Regional Polio Reference Laboratory, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Health Commission Key Laboratory of Microbial Genomics, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention & Chinese Academy of Preventive Medicine, Beijing, China.
Xiaohong ZhaoGansu Center for Disease Control and Prevention & Gansu Provincial Academy of Preventive Medicine, Lanzhou, China.
Shang GaoNational Laboratory for Poliomyelitis, WHO WPRO Regional Polio Reference Laboratory, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Health Commission Key Laboratory of Microbial Genomics, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention & Chinese Academy of Preventive Medicine, Beijing, China.
Jinbo XiaoNational Laboratory for Poliomyelitis, WHO WPRO Regional Polio Reference Laboratory, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Health Commission Key Laboratory of Microbial Genomics, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention & Chinese Academy of Preventive Medicine, Beijing, China.
Qian YangNational Laboratory for Poliomyelitis, WHO WPRO Regional Polio Reference Laboratory, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Health Commission Key Laboratory of Microbial Genomics, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention & Chinese Academy of Preventive Medicine, Beijing, China.
Jingjing XuNational Laboratory for Poliomyelitis, WHO WPRO Regional Polio Reference Laboratory, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Health Commission Key Laboratory of Microbial Genomics, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention & Chinese Academy of Preventive Medicine, Beijing, China.
Yuecong XieNational Laboratory for Poliomyelitis, WHO WPRO Regional Polio Reference Laboratory, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Health Commission Key Laboratory of Microbial Genomics, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention & Chinese Academy of Preventive Medicine, Beijing, China.
Yixin XuSchool of Basic Medicine, Shandong Second Medical University, Weifang, China.
Xinghao YeSchool of Basic Medicine, Shandong Second Medical University, Weifang, China.
Tianjiao JiNational Laboratory for Poliomyelitis, WHO WPRO Regional Polio Reference Laboratory, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Health Commission Key Laboratory of Microbial Genomics, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention & Chinese Academy of Preventive Medicine, Beijing, China.
Yong ZhangNational Laboratory for Poliomyelitis, WHO WPRO Regional Polio Reference Laboratory, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Health Commission Key Laboratory of Microbial Genomics, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention & Chinese Academy of Preventive Medicine, Beijing, China.
Dongmei YanNational Laboratory for Poliomyelitis, WHO WPRO Regional Polio Reference Laboratory, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Health Commission Key Laboratory of Microbial Genomics, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention & Chinese Academy of Preventive Medicine, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging and re-emerging infectious diseases continue to pose a persistent challenge to global public health security. As an unbiased and noninvasive population-level surveillance approach, wastewater-based epidemiology has emerged as an urban-scale monitoring tool for proactively capturing the community disease burden. In this study, metagenomic and targeted next-generation sequencing were employed to preliminarily characterize wastewater viral communities in Gansu Province from 2024 to 2026. Across the three annual sampling groups, the Simpson diversity index calculated from metagenomic taxonomic profiles showed a significant negative correlation with sampling year. Despite viral enrichment, more than 97% of sequencing reads were assigned to bacteria, likely reflecting residual nonviral nucleic acids and limitations in metagenomic classification. The wastewater virome exhibited a complex host-association spectrum, within which bacteriophages and plant-associated viruses displayed relatively stable community structures and high relative abundances. Among human pathogens, astroviruses were consistently detected at high relative abundances across all samples. Human astrovirus 1 accounted for the largest proportion, and a nearly complete genome sequence of the extraintestinal infection-associated astrovirus MLB2 was recovered. Targeted sequencing further revealed a highly structured environmental enterovirus profile dominated by the species

Indexed as

astrovirusesenterovirusGansu Provincemetagenomic sequencingtargeted next-generation sequencingwastewater

Identifiers

PMID42840097
PMCPMC13638646

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.