ArticleFrontiers in cellular and infection microbiology2026
Antimicrobial susceptibility patterns in Jalisco, Mexico: a snapshot of regional resistance (2021-2023).
Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Antimicrobial resistance (AMR) is a major global public health threat, responsible for an estimated 4.9 million deaths worldwide and associated with increased morbi-mortality, and healthcare costs. The burden is particularly high in hospital settings, where multidrug-resistant pathogens, including ESKAPE group, are prevalent. However, in Mexico, epidemiological data remain limited. This study aimed to determine the prevalence and distribution of AMR among clinically relevant bacterial pathogens isolated in three hospitals in Guadalajara, Jalisco, Mexico, and to compare resistance patterns across hospital wards and clinical specimen types. Methods: A retrospective multicenter study was conducted from January 2021 to December 2023. Bacterial identification and susceptibility tests were performed using VITEK 2 and MicroScan WalkAway systems. Results were analyzed using WHONET and interpreted according to CLSI criteria. Clinical specimens included urine, blood, biopsies, abscesses, lower respiratory tract (LRT) specimens, and sterile fluids. Species analyzed included, Results: A total of 13,336 clinical isolates were analyzed, with Conclusions: This study reveals substantial AMR burden in Guadalajara, with particularly high levels among bloodstream pathogens, non-fermenters in LRT specimens, and carbapenem-resistant
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