ArticleFrontiers in aging neuroscience2026
Kinestesia: the prefrontal EEG response to a cognitive-motor intervention is graded by baseline cognitive status.
Article in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
Background: This is a companion neurophysiological study ( Methods: Resting-state EEG was recorded before and after 30 sessions in 19 participants (9 MCI, MoCA < 26; 10 HC, MoCA 26-29). Age-referenced Z-scores were computed for eleven pre-specified clinical EEG indices using the Harmonized Functional EEG Derived Phenotypes normative pipeline (HarFEDPNorms). The primary analysis treated the 19 participants as a single sample and correlated baseline MoCA with the pre-to-post change in each index (Spearman ρ), with Benjamini-Hochberg (BH) FDR correction. We assessed robustness to educational attainment using partial correlation. Results: Eight of the eleven pre-specified indices showed a BH-corrected continuous association with baseline MoCA. The strongest were the Engagement Index (EI) and the Alpha/Beta Ratio (ABR) at Fp2 (EI: ρ = +0.704, Conclusion: In this small, uncontrolled sample, the electrocortical response to Kinestesia was graded by baseline cognitive status, with a robust prefrontal engagement effect (EI and ABR at Fp2; BH
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