ArticleFrontiers in immunology2026
CD160 mediated NK cell activation shapes host defense against acute
Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Introduction: Methods: Bulk RNA-sequencing of mock- and Results: RNA-sequencing revealed upregulation of herpesvirus entry mediator (HVEM, TNFRSF14) in infected human dermal fibroblasts, confirmed at the protein level. HVEM was functionally engaged by CD160, and CD160 blockade reduced NK cell degranulation and secretion of cytotoxic mediators in fibroblast co-cultures. CD160 deficiency impaired NK cell activation Discussion: These findings establish the HVEM-CD160 axis as a key regulator of NK cell effector function in the skin during acute
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