Evidence map›Paper›PMID 42839969›Full record

ArticleF1000Research2025

Expression status transition of

Yoshitoku Watabe, Sakurako Kobayashi, Takahiro Nakayama, Satoru Takahashi, Masaharu Yoshihara

Abstract read
In one paragraph

Article in F1000Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yoshitoku WatabeCollege of Medicine, School of Medicine and Health Sciences, University of Tsukuba, Tsukuba, Ibaraki Prefecture, Japan.ORCID https://orcid.org/0009-0007-4611-8193
Sakurako KobayashiCollege of Medicine, School of Medicine and Health Sciences, University of Tsukuba, Tsukuba, Ibaraki Prefecture, Japan.ORCID https://orcid.org/0009-0001-1242-2097
Takahiro NakayamaCollege of Medicine, School of Medicine and Health Sciences, University of Tsukuba, Tsukuba, Ibaraki Prefecture, Japan.ORCID https://orcid.org/0000-0002-4023-4560
Satoru TakahashiCollege of Medicine, School of Medicine and Health Sciences, University of Tsukuba, Tsukuba, Ibaraki Prefecture, Japan.ORCID https://orcid.org/0000-0002-8540-7760
Masaharu YoshiharaCollege of Medicine, School of Medicine and Health Sciences, University of Tsukuba, Tsukuba, Ibaraki Prefecture, Japan.ORCID https://orcid.org/0000-0002-0212-0909

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Notch signaling, especially via the Notch1 receptor, is involved in normal eye development by maintaining retinal progenitor cell state before their differentiation, although the regulatory mechanism of fine-tuned Notch1 expression is unclear. Methods: We re-analyzed publicly available human fetal retina single-cell RNA/ATAC-seq data at days 59, 74, and 78, using Seurat/Signac pipelines. Results: We observed Conclusions: By analyzing retinal cell differentiation, this study identified a putative

Indexed as

Chromatin Assembly and DisassemblyReceptor, Notch1RetinaStem CellsCell DifferentiationGene Expression Regulation, DevelopmentalHumansNOTCH1 protein, humanReceptor, Notch1differentiationepigeneticseye developmentsingle-cell ATAC-seqsingle-cell RNA-seq

Identifiers

PMID42839969
PMCPMC13637476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.