ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Intermittent Fasting Reduces Taurine Availability and Promotes Antitumor Immunity Through PERK Attenuation-Associated Paraptosis-Like Cell Death in Colorectal Cancer.
Baohui Song, Sikei Kam, Jingyi Liu, Rui Lv, Xucheng Huo, Zhanghan Chen, Yuelun Dong, Shilun Cai, Bing Li, Ruobing Ren and 2 more
Abstract read
In one paragraphArticle in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Baohui Song *Endoscopy Center, Zhongshan Hospital, Fudan University, Shanghai Digestive Endoscopy Diagnosis and Treatment Engineering Technology Research Center, Shanghai, China.ORCID https://orcid.org/0000-0002-8182-9253 Sikei Kam *Endoscopy Center, Zhongshan Hospital, Fudan University, Shanghai Digestive Endoscopy Diagnosis and Treatment Engineering Technology Research Center, Shanghai, China.ORCID https://orcid.org/0009-0006-6577-7082 Xucheng HuoEndoscopy Center, Zhongshan Hospital, Fudan University, Shanghai Digestive Endoscopy Diagnosis and Treatment Engineering Technology Research Center, Shanghai, China.ORCID https://orcid.org/0009-0008-2662-9727 Zhanghan ChenEndoscopy Center, Zhongshan Hospital, Fudan University, Shanghai Digestive Endoscopy Diagnosis and Treatment Engineering Technology Research Center, Shanghai, China.ORCID https://orcid.org/0000-0002-5767-0326 Yuelun DongEndoscopy Center, Zhongshan Hospital, Fudan University, Shanghai Digestive Endoscopy Diagnosis and Treatment Engineering Technology Research Center, Shanghai, China.ORCID https://orcid.org/0009-0006-3084-2921 Shilun CaiEndoscopy Center, Zhongshan Hospital, Fudan University, Shanghai Digestive Endoscopy Diagnosis and Treatment Engineering Technology Research Center, Shanghai, China.ORCID https://orcid.org/0009-0007-3779-4157 Bing LiEndoscopy Center, Zhongshan Hospital, Fudan University, Shanghai Digestive Endoscopy Diagnosis and Treatment Engineering Technology Research Center, Shanghai, China.
Yunshi ZhongEndoscopy Center, Zhongshan Hospital, Fudan University, Shanghai Digestive Endoscopy Diagnosis and Treatment Engineering Technology Research Center, Shanghai, China.ORCID https://orcid.org/0000-0002-3128-3168 Mingyan CaiEndoscopy Center, Zhongshan Hospital, Fudan University, Shanghai Digestive Endoscopy Diagnosis and Treatment Engineering Technology Research Center, Shanghai, China.ORCID https://orcid.org/0000-0002-8155-3154 Funding
Clinical Research Special Project of Zhongshan Hospital, Fudan University ZSLCYJ202350National Natural Science Foundation of China 62635004：82273025Shanghai Innovative Medical Devices and Pharmaceuticals Application Demonstration Project 25SF1906800Shanghai Municipal Health Commission Specialized Clinical Research Project 202340178Shanghai Municipal Health Commission Specialized Clinical Research Project 202540081
6 · The paper itselfAbstract
Intermittent fasting (IF) exerts antitumor activity in colorectal cancer (CRC), but the tumor-intrinsic metabolic mechanism linking nutrient restriction to antitumor immunity remains unclear. In this study, IF reduced taurine availability and suppressed tumor growth in a CD
Indexed as
anti‐tumor effectcolorectal cancerintermittent fastingPERKtaurinetumor microenvironment
Identifiers
PMID42839693
PMCPMC13643236
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