Observational studyImmunity, inflammation and disease2026
Trends in Aeroallergen IgE Sensitization in Jordan: A Decade-Long Observational Study.
Observational study in Immunity, inflammation and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Trends in Aeroallergen IgE Sensitization in Jordan: A Decade-Long Observational Study.Immunity, inflammation and disease · 2026Observational
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInhalant allergies from airborne allergens, such as pollen, dust mites, and animal dander, substantially contribute to allergic respiratory diseases globally. Sensitization to aeroallergens is influenced by environmental, urban, and climatic factors and demographic characteristics, including age and sex. However, long-term data from large non-disease-specific patient cohorts in Jordan are unavailable, particularly those covering the COVID-19 pandemic years.
objectiveTo characterize prevalence and patterns of aeroallergen-specific IgE (s-IgE) sensitization in Jordan over a 10-year period (2012-2022), evaluating associations with age, sex, and temporal trends.
methodsWe retrospectively analyzed 4675 serum samples from patients tested at Biolab Diagnostic Laboratories. Aeroallergen s-IgE was measured using the CE-certified EUROLINE immunoblot panel covering 29 inhalant allergens. Samples positive for cross-reactive carbohydrate determinants (2.4%) or repeat tests (3.8%) were excluded. Multivariable logistic regression assessed associations of sensitization with sex, age group (<20, 20-40, >40 years), and sample collection period (2012-2015, 2016-2019, 2020-2022).
resultsOverall, 45.5% were sensitized to ≥1 aeroallergen. Males had higher odds of sensitization than females (OR = 1.35, p < 0.0001). Sensitization was most prevalent in the 20-40-year age group. Temporal analysis showed an increase in overall sensitization from 40% in 2012-2015 to 50.6% in 2020-2022. The most common sensitizers were predominantly pollens (olive pollen being the single most prevalent at 21.9%), along with cat dander (17.5%) and dust mites (~12% combined). A mixed pattern of increased sensitization to both outdoor and indoor aeroallergens was observed during the pandemic years.
conclusionsAeroallergen sensitization in Jordan shows significant sex-, age-, and time-related patterns, with an overall increasing trend over the past decade, including during the COVID-19 pandemic. These findings provide a robust epidemiologic baseline to inform public health strategies, allergen mitigation, and clinical management in urban and regional contexts.
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