ArticleChemistry & biodiversity2026
Anti-Inflammatory Activity of Cotula cinerea Essential Oil: Integrated Chemical, In Vivo, Histological, and Computational Evaluation.
Habiba Haddad, Mohammed Larbi Benamor, Yahia Bekkar, Ouafa Boudebia, Salah Neghmouche Nacer, Elhafnaoui Lanez, Aicha Adaika, Taher M Abdelhameed, Lazhar Bechki, Touhami Lanez and 1 more
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In one paragraphArticle in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
11 authors.
Habiba HaddadFaculty of Technology, Department of Process Engineering and Petrochemistry, Laboratory of Valorisation and Technology of Saharian Resources (VTRS), University of El Oued, El Oued, Algeria.
Mohammed Larbi BenamorFaculty of Technology, Department of Process Engineering and Petrochemistry, Laboratory of Valorisation and Technology of Saharian Resources (VTRS), University of El Oued, El Oued, Algeria.ORCID https://orcid.org/0000-0002-6972-4221 Yahia BekkarFaculty of Technology, Department of Process Engineering and Petrochemistry, Laboratory of Valorisation and Technology of Saharian Resources (VTRS), University of El Oued, El Oued, Algeria.ORCID https://orcid.org/0000-0001-5816-2043 Ouafa BoudebiaFaculty of Technology, Department of Process Engineering and Petrochemistry, Laboratory of Valorisation and Technology of Saharian Resources (VTRS), University of El Oued, El Oued, Algeria.
Elhafnaoui LanezFaculty of Technology, Department of Process Engineering and Petrochemistry, Laboratory of Valorisation and Technology of Saharian Resources (VTRS), University of El Oued, El Oued, Algeria.ORCID https://orcid.org/0000-0002-6543-2547 Aicha AdaikaFaculty of Technology, Department of Process Engineering and Petrochemistry, Laboratory of Valorisation and Technology of Saharian Resources (VTRS), University of El Oued, El Oued, Algeria.ORCID https://orcid.org/0000-0002-7829-709X Lazhar BechkiFaculty of Mathematics and Material Sciences, Department of Chemistry, Laboratory of Valorisation and Promotion of Saharan Resources (VPRS), Kasdi Merbah University, Ouargla, Algeria.ORCID https://orcid.org/0000-0002-2242-8310 Touhami LanezFaculty of Technology, Department of Process Engineering and Petrochemistry, Laboratory of Valorisation and Technology of Saharian Resources (VTRS), University of El Oued, El Oued, Algeria.ORCID https://orcid.org/0000-0002-3978-7635 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
The anti-inflammatory activity of Cotula cinerea essential oil (EO) was evaluated using integrated chemical, in vivo, histological, and computational approaches. Gas chromatography-mass spectrometry (GC-MS) identified trans-thujone (51.86%), santolina triene (10.60%), and sabinene (6.17%) as the most abundant constituents. In benzylthiouracil (BTU)-treated Wistar rats, EO administration reduced the liver and kidney indices from 4.36% to 2.70% and from 0.65% to 0.52%, respectively; red blood cell count increased from 4.90 to 7.17 × 10
Indexed as
Anti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalOils, VolatileAnimalsCyclooxygenase 2Gas Chromatography-Mass SpectrometryKidneyLiverMaleMolecular Docking SimulationRatsRats, WistarAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalCyclooxygenase 2Oils, Volatileanti‐inflammatoryCotula cinereaessential oilGC‐MShistopathological analysisMM‐PBSAmolecular dockingmolecular dynamics
Identifiers
PMID42836422
PMCPMC13640041
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