Evidence map›Paper›PMID 42836417›Full record

ArticleAnatomical record (Hoboken, N.J. : 2007)2026

Biomechanical strain patterns in Meckel's cartilage underlie mandibular variation in FGFR2 mouse models.

Fred R Foster, Alexandre Freire, Ana Cláudia Rossi, Jordan Wilson, Joan T Richtsmeier, Kazuhiko Kawasaki, Felippe B Prado, Susan M Motch Perrine

Abstract read
In one paragraph

Article in Anatomical record (Hoboken, N.J. : 2007), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fred R FosterDepartment of Anthropology, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0009-0003-7545-3733
Alexandre FreireDepartment of Biosciences, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, Brazil.ORCID https://orcid.org/0000-0002-0175-0896
Ana Cláudia RossiDepartment of Biosciences, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, Brazil.ORCID https://orcid.org/0000-0002-8718-4898
Jordan WilsonDepartment of Anthropology, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-3837-4596
Joan T RichtsmeierDepartment of Anthropology, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-0239-5822
Kazuhiko KawasakiDepartment of Anthropology, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-1090-5340
Felippe B PradoDepartment of Biosciences, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, Brazil.ORCID https://orcid.org/0000-0001-5636-6915
Susan M Motch PerrineDepartment of Anthropology, The Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-3412-221X

Funding

Cartilage and bone of the lower jaw in development and diseaseR01DE031439 · NIDCR · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI Ethylin Wang Jabs, Kazuhiko Kawasaki · 2022 to 2026
$3.8M
Genetic, Tissue, and Anatomical Interactions in Mandibulofacial DysmorphogenesisR01DE029832 · NIDCR · MAYO CLINIC ROCHESTER · PI JABS, ETHYLIN WANG, KAWASAKI, KAZUHIKO · 2021 to 2024
$2.9M
NIDCR NIH HHS DE029832NIDCR NIH HHS DE031439NIDCR NIH HHS R01 DE029832NIDCR NIH HHS R01 DE031439
6 · The paper itself

Abstract

Sequence variations in fibroblast growth factor receptor 2 (FGFR2) are associated with craniosynostosis syndromes, disrupting craniofacial development, yet early mandibular alterations remain poorly characterized. This study examined Meckel's cartilage (MC) and mandibular morphology in mouse models of Apert (Fgfr2

Indexed as

biomechanical modelingcraniosynostosis syndromesFGFR2 sequence variantsmandibular morphologyMeckel's cartilage development

Identifiers

PMID42836417
PMCPMC13688089

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.