Evidence map›Paper›PMID 42836260›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2026

Stereo Cherenkov imaging as 3D absolute dose monitoring tool for total skin electron therapy (TSET).

Yifeng Zhu, Baozhu Lu, Emily Xiong, Ching Lai, Karen Tang, Harper G Hubbeling, John P Plastaras, Michael LaRiviere, Brian W Pogue, Timothy C Zhu

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yifeng ZhuDept. of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
Baozhu LuDept. of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
Emily XiongDept. of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
Ching LaiDept. of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
Karen TangDept. of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
Harper G HubbelingDept. of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
John P PlastarasDept. of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
Michael LaRiviereDept. of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
Brian W PogueDepartment of Biomedical Engineering, Dartmouth College, Hanover, NH 03755.
Timothy C ZhuDept. of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.

Funding

Cherenkov imaging incorporating 3D surface imaging for TSETR01CA274411 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ZHU, TIMOTHY C. · 2022 to 2025
$2.1M
NCI NIH HHS R01 CA274411
6 · The paper itself

Abstract

Cherenkov imaging provides a non-contact method for monitoring surface dose delivery during total skin electron therapy (TSET), where patients are treated in six postures using the Stanford standing technique. In this study, a multi-view Cherenkov imaging framework combined with patient-specific correction factors was investigated to improve quantitative three-dimensional (3D) surface dose estimation. Cherenkov emission was recorded during treatment using three synchronized time-gated cameras providing anterior and lateral coverage. Patient-specific anatomical models reconstructed from 3D surface scans were used to generate Monte Carlo (MC) reference dose distributions. Cherenkov images were corrected for background, camera response, and geometric distortions before conversion to pseudo-dose using in-vivo dosimetry calibration. Vertical Cherenkov intensity profiles were compared with MC dose profiles to derive patient-specific correction factors. Results showed that uncorrected Cherenkov-derived dose underestimated dose in distal and lateral body regions, while applying patient-specific corrections and multi-view imaging improved agreement with MC reference dose, supporting enhanced surface dose monitoring for TSET.

Indexed as

biomedical opticsCherenkov imagingcomputer graphicstotal skin electron therapy

Identifiers

PMID42836260
PMCPMC13638229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.