Evidence map›Paper›PMID 42836177›Full record

ArticleOxford medical case reports2026

A diagnostic dilemma: autoimmune pulmonary alveolar Proteinosis unmasked by vaping-induced lung injury.

Mohammed Najdat Seijari, Taraneh Zamani, Mohammad Nasser Affas, Souwdamini Sethuram, Marwa Alfaraj, Muhammad Umair Khawar

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxford medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammed Najdat SeijariDepartment of Internal Medicine, TriHealth, Good Samaritan Hospital, 375 Dixmyth Avenue, Cincinnati, OH 45220, United States.ORCID https://orcid.org/0000-0001-6189-2784
Taraneh ZamaniDepartment of Internal Medicine, TriHealth, Good Samaritan Hospital, 375 Dixmyth Avenue, Cincinnati, OH 45220, United States.
Mohammad Nasser AffasDepartment of Internal Medicine, Hamad Medical Corporation, Hamad Medical City, Doha, Qatar.
Souwdamini SethuramDepartment of Internal Medicine, TriHealth, Good Samaritan Hospital, 375 Dixmyth Avenue, Cincinnati, OH 45220, United States.
Marwa AlfarajFaculty of Medicine, Damascus University, Al-Mazzeh Street, Damascus, Syria.
Muhammad Umair KhawarDepartment of Pulmonary and Critical Care Medicine, TriHealth, Good Samaritan Hospital, 375 Dixmyth Avenue, Cincinnati, OH 45220, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 65-year-old smoker with recent vaping resumption, found to have elevated anti-GM-CSF antibodies suggestive of autoimmune pulmonary alveolar proteinosis (PAP). However, bronchoalveolar lavage and whole lung lavage were inconclusive, raising suspicion for concurrent E-cigarettes or vaping-associated lung injury (EVALI). The patient showed no clinical response to corticosteroids and eventually passed away. Post-mortem pathology confirmed surfactant accumulation and foamy macrophages but also showed features of diffuse alveolar damage. This case underscores the diagnostic and management challenges when PAP and inhalational lung injuries overlap.

Indexed as

diffuse alveolar damagepulmonary alveolar Proteinosisvaping-induced lung injury

Identifiers

PMID42836177
PMCPMC13637815

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.