Evidence map›Paper›PMID 42836113›Full record

ArticlePeerJ2026

Body mass index-stratified inflammatory predictors of insulin resistance in non-obese adults: a retrospective study.

Aycan Acet, Turkan Pasali Kilit, Sertas Erarslan, Cumali Yalçın, Can Özlü, Çağla Özdemir

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Article in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Aycan AcetFaculty of Medicine, Departmant of Internal Medicine, Kütahya Health Sciences University, Kütahya, Turkey.
Turkan Pasali KilitFaculty of Medicine, Departmant of Internal Medicine, Kütahya Health Sciences University, Kütahya, Turkey.
Sertas ErarslanFaculty of Medicine, Departmant of Internal Medicine, Kütahya Health Sciences University, Kütahya, Turkey.
Cumali YalçınFaculty of Medicine, Departmant of Internal Medicine, Division of Hematology, Kütahya Health Sciences University, Kütahya, Turkey.
Can ÖzlüFaculty of Medicine, Departmant of Internal Medicine, Division of Hematology, Kütahya Health Sciences University, Kütahya, Turkey.
Çağla ÖzdemirFaculty of Medicine, Departmant of Family Medicine, Kütahya Health Sciences University, Kütahya, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Insulin resistance (IR) is a key mechanism underlying type 2 diabetes mellitus and cardiometabolic disease. Although obesity-related inflammation is a major contributor to IR, increasing evidence indicates that IR may also develop in non-obese individuals. However, readily available inflammatory markers applicable to this population remain limited. We evaluated the association between inflammatory markers and insulin resistance in non-obese adults and assessed their predictive performance across body mass index (BMI) strata. Methods: This retrospective cross-sectional study included 149 non-obese adults (BMI < 30 kg/m Results: Insulin resistance was identified in 54 participants (36.2%). Individuals with IR had higher white blood cell (WBC) counts, CRP levels, and CRP/HDL ratios (all Conclusions: Low-grade systemic inflammation is independently associated with insulin resistance in non-obese adults, with distinct inflammatory predictors across BMI categories. WBC count may reflect early immune activation in normal-weight individuals, whereas the CRP/HDL ratio appears more informative among overweight subjects.

Indexed as

Body Mass IndexInflammationInsulin ResistanceAdultAgedBiomarkersCholesterol, HDLC-Reactive ProteinCross-Sectional StudiesFemaleHumansLeukocyte CountMaleMiddle AgedRetrospective StudiesBiomarkersCholesterol, HDLC-Reactive ProteinBody mass indexCRP/HDL ratioInflammationInsulin resistanceNon-obese adultsWhite blood cell count

Identifiers

PMID42836113
PMCPMC13637635

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.