ArticleJournal of the colleges of medicine of South Africa2026
Outcomes of suture-assisted gonioscopy-assisted transluminal trabeculotomy in a cohort of South African patients with primary open-angle glaucoma.
Article in Journal of the colleges of medicine of South Africa, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Gonioscopy-assisted transluminal trabeculotomy (GATT) is a minimally invasive glaucoma surgery that enhances trabecular outflow by circumferentially incising Schlemm's canal. Internationally, studies have reported favourable outcomes, but evidence from South African patients remains limited. This study evaluated the effectiveness and safety of GATT in South African patients with primary open-angle glaucoma (POAG). Methods: A retrospective cohort study was conducted at Eerste River Hospital. Patients with POAG who underwent GATT between August 2020 and November 2022 were followed for 24 months. They were divided into two groups: combined phacoemulsification and GATT (Group I) and standalone GATT (Group II). Demographic characteristics, intraocular pressure (IOP), glaucoma medication use, and postoperative complications were collected. Results: Fifty-two patients ( Conclusion: Gonioscopy-assisted transluminal trabeculotomy, performed alone or combined with phacoemulsification, was an effective and safe option for lowering IOP in South African patients with POAG. The sustained IOP reduction, decreased medication burden and favourable safety profile support its use, particularly in resource-limited settings. Contribution: This study provides region-specific evidence on the outcomes and safety of GATT in a South African POAG cohort.
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