Evidence map›Paper›PMID 42835982›Full record

ArticleGynecologic oncology reports2026

Barriers to the recognition and evaluation of abnormal uterine bleeding among individuals at increased risk for endometrial Cancer.

Shariska P Harrington, Negar Taheri, Manisha Salinas, Andilyn Mehltretter, Nicholas McConnell, Martha O'Neill, Arushi Agarwal, Donna Hochberg, Tomasz Beer, Mark Camardo and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gynecologic oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shariska P HarringtonDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Mayo Clinic, Rochester, MN, USA.
Negar TaheriDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Mayo Clinic, Rochester, MN, USA.
Manisha SalinasCenter for Health Equity and Community Engaged Research, Mayo Clinic, Jacksonville, FL, USA.
Andilyn MehltretterHealth Advances, 275 Grove Street 1E-Suite 310, Newton, MA 02466, USA.
Nicholas McConnellHealth Advances, 275 Grove Street 1E-Suite 310, Newton, MA 02466, USA.
Martha O'NeillHealth Advances, 275 Grove Street 1E-Suite 310, Newton, MA 02466, USA.
Arushi AgarwalHealth Advances, 275 Grove Street 1E-Suite 310, Newton, MA 02466, USA.
Donna HochbergHealth Advances, 275 Grove Street 1E-Suite 310, Newton, MA 02466, USA.
Tomasz BeerExact Sciences, 5505 Endeavor Lane, Madison, WI 53719, USA.
Mark CamardoExact Sciences, 5505 Endeavor Lane, Madison, WI 53719, USA.
Elle Kielar-GrevstadExact Sciences, 5505 Endeavor Lane, Madison, WI 53719, USA.
Jamie N Bakkum-GamezDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Mayo Clinic, Rochester, MN, USA.

Funding

Paul Calabresi Program in Clinical/Translational Research at Mayo ClinicK12CA090628 · NCI · MAYO CLINIC ROCHESTER · PI WEROHA, SARAVUT · 2001 to 2025
$19.7M
NCI NIH HHS K12 CA090628
6 · The paper itself

Abstract

Objective: To evaluate knowledge of abnormal uterine bleeding (AUB) and postmenopausal bleeding (PMB) as symptoms of endometrial cancer (EC), assess understanding of diagnostic evaluation, and identify barriers and facilitators to care. Methods: We conducted a web-based survey of participants ( Results: Although 78% recognized abnormal bleeding within six months, 21% reported delayed recognition and 25% had not sought evaluation. Only 12% identified AUB/PMB as a potential symptom of cancer, with participants aged ≥45 years less likely to make this association. While 75% sought medical care, 28% reported that their healthcare provider was not concerned about their bleeding; among these participants, 60% reported experiencing symptom dismissal. Familiarity with endometrial biopsy was lower among Medicaid-insured participants (OR 0.50, 95% CI 0.33-0.77). More convenient testing options increased self-reported motivation to seek evaluation. Conclusions: Knowledge gaps, delayed symptom recognition, and experiences of symptom dismissal identify potential barriers along the pathway to evaluation of abnormal bleeding.

Indexed as

Abnormal uterine bleedingDiagnostic evaluationEndometrial cancerSurvey

Identifiers

PMID42835982
PMCPMC13636334

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.