ArticleFrontiers in psychiatry2026
Possible drivers of self-harm severity - relative contributions of post-traumatic stress and levels of personality functioning - results from the Extreme Challenges project.
Article in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Self-harm (SH) is common, but its severity varies. Severe cases may involve extensive hospitalization and high suicide risk. Although SH is associated with post-traumatic stress disorder (PTSD), personality disorder (PD), and complex cases of PD-PTSD comorbidity, factors related to SH severity are sparsely researched. Aims: The study aims to investigate how SH severity relates to PTSD symptoms and different domains of personality functioning. The study also aims to explore indirect associations of interpersonal functioning, PTSD symptoms and SH severity. Methods: In a multicenter cross-sectional design, the study included outpatients admitted for personality disorder treatment ( Results: More severe PTSD symptoms and poorer self-functioning (self-control and identity integration) were significantly and independently associated with greater SH severity. The association between PTSD symptoms and increasing SH severity was partially mediated by greater impairment of self-control and identity integration. Interpersonal domains were not associated with SH severity. Conclusion: This study highlights post-traumatic stress and personality problems as common clusters of symptoms among patients with increasingly severe SH. Further exploration indicated personality functioning self-domains as potential drivers of the association between post-traumatic symptoms and SH severity. Results support integrated, individualized treatment addressing SH in light of both trauma burden and personality functioning.
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