Evidence map›Paper›PMID 42835716›Full record

ReviewFrontiers in pharmacology2026

uPAR-directed immunotherapies in solid tumors: current advances and future perspectives.

Filomena Napolitano, Nunzia Montuori

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Filomena NapolitanoDepartment of Translational Medical Sciences, University of Naples Federico II, Naples, Italy.
Nunzia MontuoriDepartment of Translational Medical Sciences, University of Naples Federico II, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In cancer, elevated expression of the urokinase-type plasminogen activator receptor (uPAR) is a well-established adverse prognostic factor associated with enhanced tumor invasion, metastatic dissemination, cellular proliferation, and resistance to conventional therapies. Genetic ablation or silencing of uPAR has been shown to impair multiple protumorigenic functions both

Indexed as

CAR T cell therapyimmunotherapysolid tumorsuPARurokinase plasminogen activator receptor

Identifiers

PMID42835716
PMCPMC13635701

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.