ArticleToxicology reports2026
Effects of lawsone and lawsone methyl ether on cyclooxygenase activity, redox balance, and organ-specific toxicity: An integrated computational and experimental study.
Article in Toxicology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
Redox imbalance contributes significantly to the initiation and progression of inflammatory responses. Although conventional anti-inflammatory drugs are widely used, their prolonged administration is associated with a number of adverse effects. Lawsone methyl ether (LME) and lawsone are plant-derived, redox-active naphthoquinones, exhibiting diverse pharmacological activities; however, their cyclooxygenase (COX)-inhibitory effects, redox-modulatory properties, and oral toxicity profiles remain insufficiently characterized. Therefore, this study investigated the COX-inhibitory activity, redox-modulatory effects, and oral toxicity profiles of LME and lawsone using integrated computational, enzyme-inhibitory, and
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