Evidence map›Paper›PMID 42835638›Full record

ArticleClinical case reports2026

Utility of Metagenomic Next-Generation Sequencing in Identifying Anaerobic Pathogens in a Pediatric Brain Abscess Secondary to Sinusitis: A Case Report.

Risa Nagase, Kunihiro Oba, Mari Asakura, Masashi Ogasawara, Masahiro Noda, Yusuke Yamada, Asayo Furukawa, Naoki Kojima, Masanori Hashino, Kazuhiro Horiba

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Risa NagaseDepartment of Pediatrics Showa General Hospital Kodaira Japan.ORCID https://orcid.org/0009-0005-0553-4778
Kunihiro ObaDepartment of Pediatrics Showa General Hospital Kodaira Japan.
Mari AsakuraDepartment of Pediatrics Showa General Hospital Kodaira Japan.
Masashi OgasawaraDepartment of Pediatrics Showa General Hospital Kodaira Japan.ORCID https://orcid.org/0000-0001-6766-4029
Masahiro NodaDepartment of Pediatrics Showa General Hospital Kodaira Japan.
Yusuke YamadaDepartment of Neurosurgery Showa General Hospital Kodaira Japan.
Asayo FurukawaDepartment of Otolaryngology Showa General Hospital Kodaira Japan.
Naoki KojimaDepartment of Critical Care and Emergency Medicine Showa General Hospital Kodaira Japan.
Masanori HashinoLaboratory of Microbial Genomics, Pathogen Genomics Center National Institute of Infectious Diseases, Japan Institute for Health Security Shinjuku-ku Japan.
Kazuhiro HoribaLaboratory of Microbial Genomics, Pathogen Genomics Center National Institute of Infectious Diseases, Japan Institute for Health Security Shinjuku-ku Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this pediatric brain abscess case, metagenomic next-generation sequencing (mNGS) identified an anaerobic bacterium that remained undetected using conventional culture methods, thus providing clinically relevant information for antimicrobial management. This indicates that mNGS may be a useful adjunct for optimizing treatment strategies.

Indexed as

anaerobic infectionbrain abscessmetagenomic next‐generation sequencingpediatricsinusitis

Identifiers

PMID42835638
PMCPMC13635625

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.