Evidence map›Paper›PMID 42835426›Full record

ArticleExperimental and therapeutic medicine2026

Prognostic significance of the blood urea nitrogen-to-serum albumin ratio in patients with septic shock.

Jianhua Liu, Zhengxiang Wei, Sheng Ye, Min Shao

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Article in Experimental and therapeutic medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jianhua LiuDepartment of Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China.
Zhengxiang WeiDepartment of Critical Care Medicine, The Affiliated Chuzhou Hospital of Anhui Medical University (The First People's Hospital of Chuzhou), Chuzhou, Anhui 239000, P.R. China.
Sheng YeSchool of Smart Materials and Future Energy, Anhui Normal University, Wuhu, Anhui 241002, P.R. China.
Min ShaoDepartment of Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The blood urea nitrogen-to-serum albumin ratio (BAR) has been linked to clinical outcomes in multiple critical illnesses; however, its prognostic value in patients with septic shock remains inconclusive. The present retrospective observational study involved 120 patients with septic shock, who were classified into a survivor group (n=97) and a non-survivor group (n=23) based on discharge outcomes. Within 24 h of ICU admission, important clinical and laboratory data were collected and compared between the two groups. Multivariate logistic regression analysis identified BAR [odds ratio (OR)=1.052; 95% confidence interval (CI):1.014-1.117; P=0.012] and the Acute Physiology and Chronic Health Evaluation II (APACHE II; OR=1.096; 95% CI:1.014-1.185; P=0.030) as independent risk factors for in-hospital mortality in these patients. Receiver operating characteristic (ROC) curve analysis showed that the area under the curve (AUC) of BAR for predicting in-hospital mortality was 0.707. At the optimal cutoff value of 13.62, BAR had a sensitivity of 73.9% and a specificity of 63.9%. Further, the AUC of the multivariable model [including BAR, diastolic blood pressure (DBP), APACHE II, and partial pressure of carbon dioxide (PCO

Indexed as

biomarkerblood urea nitrogen-to-serum albumin ratiopredictive valueprognosisseptic shock

Identifiers

PMID42835426
PMCPMC13635834

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