Evidence map›Paper›PMID 42835230›Full record

ArticleiLIVER2026

Preoperative MRI-derived fat fraction is linked to survival after liver transplantation for hepatocellular carcinoma.

Jialin Gao, Donghua Zhang, Tao Jiang, Decai Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iLIVER, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jialin GaoDivision of Hepatobiliary and Transplantation Surgery, Department of General Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China.
Donghua ZhangDepartment of General Surgery, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China.
Tao JiangDepartment of General Surgery, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China.
Decai YuDivision of Hepatobiliary and Transplantation Surgery, Department of General Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Liver transplantation (LT) is a curative option for hepatocellular carcinoma (HCC). However, HCC recurrence and the limited accuracy of current morphological criteria remain unresolved issues. This study investigated the association between preoperative magnetic resonance imaging (MRI)-derived fat fraction (FF) and survival in patients with HCC undergoing LT. Methods: We retrospectively reviewed 42 patients with HCC who underwent orthotopic LT. Preoperative FF was obtained from dual-echo T1-weighted imaging, and patients were categorized into low- ( Results: Baseline characteristics were comparable between the two groups, except for higher cholesterol level in the low-FF group. Elevated alpha-fetoprotein level (≥40 ng/mL) was independently associated with shorter DFS (hazard ratio [HR] = 3.649; 95% confidence interval [CI]: 1.002-13.289; Conclusion: Preoperative MRI-derived FF is independently associated with DSS after LT in patients with HCC. FF assessment may complement the Milan criteria and improve candidate selection, thereby supporting clinical decision-making.

Indexed as

Fat fractionHepatocellular carcinomaLiver transplantationMagnetic resonance imagingPrognosis

Identifiers

PMID42835230
PMCPMC13634980

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.