SynthesisFrontiers in medicine2026
Efficacy and safety of early mobilization in patients with ARDS: a systematic review and meta-analysis.
Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate the effect of early mobilization in patients with acute respiratory distress syndrome (ARDS). Methods: Computerized searches were conducted in PubMed, EMbase, The Cochrane Library, Web of Science, CNKI, Wanfang Data, CBM, and VIP databases for randomized controlled trials (RCTs) on early mobilization in ARDS patients. The retrieval period was from the establishment of each database to September 30, 2025. Two reviewers independently assessed the quality of included literature and extracted data in accordance with Cochrane systematic review methodology. Meta-analysis was performed using RevMan 5.4.1 software for eligible studies. Results: A total of 7 RCTs were included, consisting of 4 English and 3 Chinese articles. Meta-analysis showed that compared with conventional treatment, early mobilization significantly reduced the incidence of intensive care unit-acquired weakness (ICU-AW) [OR = 0.35, 95% CI (0.19,0.64), Conclusion: Early mobilization yields significant clinical benefits for ARDS patients, improving short-term clinical outcomes and functional recovery. It is worthy of clinical promotion and application. However, multicenter, large-sample, and methodologically standardized RCTs are still needed to further verify its long-term effects and optimal implementation protocols.
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