Evidence map›Paper›PMID 42835166›Full record

ArticleFrontiers in molecular biosciences2026

H

Robert Robergs, Marek Nalos, Petr Kelbich, Adela Jizerová, Ivana Mervartová, Michal Vostrý, Milan Štengl, Vaclav Babuška

Abstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Robert RobergsFaculty of Health Studies, Jan Evangelista Purkyné University, Ústínad Labem, Czech Republic.
Marek NalosDepartment of Intensive Care Medicine, Pilsen Hospital and Charles University, Pilsen, Czech Republic.
Petr KelbichDepartment of Biomedicine and Laboratory Diagnostics, Faculty of Health Studies, Jan Evangelista Purkyné University and Masaryk Hospital in Ústínad Labem, Ústínad Labem, Czech Republic.
Adela JizerováDepartment of Biomedicine and Laboratory Diagnostics, Faculty of Health Studies, Jan Evangelista Purkyné University and Masaryk Hospital in Ústínad Labem, Ústínad Labem, Czech Republic.
Ivana MervartováDepartment of Environmental Chemistry, Jan Evangelista Purkyné University, Ústínad Labem, Czech Republic.
Michal VostrýFaculty of Health Studies, Jan Evangelista Purkyné University, Ústínad Labem, Czech Republic.
Milan ŠtenglDepartment of Physiology, Faculty of Medicine, Charles University, Pilsen, Czech Republic.
Vaclav BabuškaDepartment of Medical Chemistry and Biochemistry, Faculty of Medicine, Charles University, Pilsen, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Despite animal research of cellular and systemic acidosis for more than 100 years, there is no dominant evidence-based understanding of the cause of metabolic acidosis. Embedded in this crisis state is the understanding that the hydrogen ion (H Methods: Reagents were prepared using deionized water, substrates at known concentrations, enzymes and needed activator chemicals. The chemical reactions studied were creatine kinase (CKase) (to ATP and CrP), ATPase, hexokinase (HKase), and glucose-6-phosphate dehydrogenase (G Results: Results are presented as start pH:end pH; [Product], mmol·L Conclusions: The evidence opposes traditional theories as the sole cause of cellular or systemic acidosis.

Indexed as

acidosisalkalosisbioenergeticsbufferingenzymologymetabolism

Identifiers

PMID42835166
PMCPMC13634964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.