Evidence map›Paper›PMID 42835098›Full record

ArticleKidney international reports2026

Leveraging Natural Language Processing to Identify Variation in Kidney Transplant Access.

Sri Lekha Tummalapalli, Matthew Manganel, Will Simmons, Jonathan Lin, Braja Gopal Patra, Prakash Adekkanattu, Nivedita Chang, Margaret M Fabiszak, Daniel M Levine, Yifan Peng and 3 more

Abstract read
In one paragraph

Article in Kidney international reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sri Lekha TummalapalliDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.
Matthew ManganelResearch Informatics, Division of Information Technologies and Services, Weill Cornell Medicine, New York, New York, USA.
Will SimmonsDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.
Jonathan LinDivision of Nephrology, Hypertension, & Transplantation, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
Braja Gopal PatraDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.
Prakash AdekkanattuResearch Informatics, Division of Information Technologies and Services, Weill Cornell Medicine, New York, New York, USA.
Nivedita ChangResearch Informatics, Division of Information Technologies and Services, Weill Cornell Medicine, New York, New York, USA.
Margaret M FabiszakDepartment of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Daniel M LevineThe Rogosin Institute, New York, New York, USA.
Yifan PengDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.
Evan SholleDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.
Jeffrey SilberzweigDivision of Nephrology, Hypertension, & Transplantation, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
Deirdre SawinskiThe Rogosin Institute, New York, New York, USA.

Funding

AHRQ HHS K08 HS028684
6 · The paper itself

Abstract

Introduction: There are significant sex, racial, ethnic, and socioeconomic disparities in kidney transplantation in the United States, but upstream factors driving these disparities are understudied because prewaitlisting data are not yet routinely collected by national data surveillance systems. Methods: To address this gap, we developed a rule-based semiautomated natural language processing (NLP) pipeline to extract prewaitlist milestones from nephrologist and social worker clinical notes at a nonprofit dialysis organization in New York City. Our outcomes were (i) transplant discussed with the patient; (ii) patient interest in transplant; (iii) transplant referral; and (iv) receipt of a kidney transplant. In a retrospective observational cohort study of patients with incident end-stage kidney disease (ESKD) receiving dialysis, we evaluated sex-based, racial and ethnic, and socioeconomic variation (on the basis of primary insurance payer and census block group-level Area Deprivation Index [ADI]) in the outcomes of interest using multivariable logistic regression and Cox models. Results: Our NLP pipeline showed excellent precision, recall, and F1 scores > 0.8. Among 2624 patients, documentation of transplant discussion (adjusted subhazard ratio [sHR]: 1.30; 95% confidence interval [CI]: 1.01-1.67) and patient interest (sHR: 2.11; 95% CI: 1.65-2.69) were associated with a greater likelihood of receiving a kidney transplant. Patients with Medicaid (vs. non-Medicaid, adjusted odds ratio [OR]: 0.73; 95% CI:, 0.59-0.90) were less likely to have interest in transplant documented. Sex, race and ethnicity, and ADI were not associated with time to transplant referral in adjusted analyses. Non-Hispanic Black race (adjusted sHR: 0.40; 95% CI: 0.23-0.69), Medicaid insurance (adjusted sHR: 0.73; 95% CI: 0.56-0.94), and below-median ADI (adjusted sHR: 0.77; 95% CI: 0.60-0.98) were associated with lower receipt of a kidney transplant. Conclusions: Using a novel NLP pipeline, we identified socioeconomic disparities in the documentation of patient interest in transplant, but not referrals. Patient-level interventions to increase interest in transplantation may be needed to address disparities in kidney transplantation.

Indexed as

dialysisend-stage kidney diseaseend-stage renal diseasekidney transplantnatural language processingtransplant referral

Identifiers

PMID42835098
PMCPMC13634884

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.