Evidence map›Paper›PMID 42835097›Full record

ArticleVeterinary and animal science2026

Changes in ruminal lipopolysaccharide, fermentation characteristics, nutrient digestibility, blood variables, and microbiota in sheep with subacute ruminal acidosis and its regulation by polymyxin CP7.

Shuai Jiao, Baozhen Zhu, Fei Li, Zhiyuan Ma, Fadi Li, Xiuxiu Weng, Ying Yu, Ping Li, Rui Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary and animal science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shuai JiaoState Key Laboratory of Grassland Agro-ecosystems, Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Rural Affairs, Engineering Research Center of Grassland Industry, Ministry of Education, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, 730020, China.
Baozhen ZhuState Key Laboratory of Grassland Agro-ecosystems, Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Rural Affairs, Engineering Research Center of Grassland Industry, Ministry of Education, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, 730020, China.
Fei LiState Key Laboratory of Grassland Agro-ecosystems, Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Rural Affairs, Engineering Research Center of Grassland Industry, Ministry of Education, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, 730020, China.
Zhiyuan MaState Key Laboratory of Grassland Agro-ecosystems, Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Rural Affairs, Engineering Research Center of Grassland Industry, Ministry of Education, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, 730020, China.
Fadi LiState Key Laboratory of Grassland Agro-ecosystems, Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Rural Affairs, Engineering Research Center of Grassland Industry, Ministry of Education, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, 730020, China.
Xiuxiu WengState Key Laboratory of Grassland Agro-ecosystems, Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Rural Affairs, Engineering Research Center of Grassland Industry, Ministry of Education, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, 730020, China.
Ying YuGansu Olymbel Biotechnology Co., Ltd, Zhangye, 734000, China.
Ping LiGansu Olymbel Biotechnology Co., Ltd, Zhangye, 734000, China.
Rui XuGansu Kunlun Biochemical Co., Ltd, Zhangye, 734000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objectives of this study were to (1) determine the effects of induced subacute ruminal acidosis (SARA) on ruminal lipopolysaccharide (LPS), nutrient apparent digestibility, ruminal fermentation parameters, hematological indices, and ruminal microbiota; and (2) evaluate the responses associated with polymyxin CP7 supplementation during SARA in Hu sheep. Eight rumen-fistulated Hu sheep sequentially underwent three 29-day stages: a control stage (CON, basal diet), a SARA induction stage (SAR, high-barley diet), and a bacteriocin-supplemented stage (BAC, high-barley diet with 500 mg/kg polymyxin CP7). The sequential design was adopted because SARA is not immediately reversible, rendering crossover designs problematic due to potential carry-over effects. Rumen pH remained below 5.60 for 315 min/d during the SAR stage, fulfilling the diagnostic criteria for SARA. Ruminal LPS concentration in the SAR stage was higher than that in the CON and BAC stages (

Indexed as

Blood indexLipopolysaccharideMicrofloraPolymyxin CP7Rumen fermentation

Identifiers

PMID42835097
PMCPMC13635255

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.