A bacteria-releasing mucoadhesive sheet for localized delivery and penetrative therapy of gastrointestinal cancer.

Jihun Lee, Sana Ashraf, Eunji Kim, Hyo-Jin Lee, Joowon Park, Heung Jin Jeon, SeungBeum Suh, Sukho Park

Abstract read

In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jihun LeeDepartment of Robotics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, 42988, Republic of Korea.

Sana AshrafBionics Research Center, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.

Eunji KimDepartment of Medical Science, College of Medicine, Chungnam National University, Daejeon, 35015, Republic of Korea.

Hyo-Jin LeeDepartment of Medical Science, College of Medicine, Chungnam National University, Daejeon, 35015, Republic of Korea.

Joowon ParkSchool of Electrical and Electronic Engineering, University of Ulsan, Ulsan, 44610, Republic of Korea.

Heung Jin JeonCancer Research Institute, Chungnam National University, Daejeon, 34134, Republic of Korea.

SeungBeum SuhBionics Research Center, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.

Sukho ParkDepartment of Robotics Engineering, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, 42988, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria-based cancer therapy shows promise for solid tumors, but effective localization and long-term retention in the gastrointestinal (GI) tract remain limited by peristalsis and fluid flow. We developed a Bacteria-Releasing Mucoadhesive Sheet (BRMS), a deployable multilayered platform for precise localized, active bacterial delivery. The BRMS consists of three functional layers: an unrolling layer for rapid deployment and conformal adhesion to the mucosa; a guard layer to minimize bacterial loss and enforce unidirectional release; and a therapeutic layer loaded with engineered

Indexed as

Engineered bacteriaGastrointestinal cancer therapyLocalized tumor treatmentTherapeutic bacterial delivery

Identifiers

PMID42835091

DOI10.1016/j.mtbio.2026.103710

PMCPMC13635254

What OpenQuestion holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.