ArticleiScience2026
One year follow up outcomes of endoscopic retrograde appendicitis treatment for symptomatic appendicoliths.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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10 authors.
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Abstract
Symptomatic appendicoliths may cause recurrent abdominal pain or distension, but appendix-preserving treatment options are limited. We retrospectively evaluated endoscopic retrograde appendicitis treatment (ERAT) in 78 patients with CT- or ultrasound-confirmed appendicoliths. Symptoms were assessed using a modified abdominal pain or distension questionnaire (APQ), and outcomes were evaluated separately in adults and minors. APQ scores decreased at 1 week, 1 month, 6 months, and 1 year after ERAT. At 1 year, complete remission was achieved in 37 of 47 adults (78.7%) and 27 of 31 minors (87.1%). Multivariable Cox regression identified disease duration longer than 3 months and fecalith lumps as predictors of incomplete remission in adults, whereas NLR > 1.87 was inversely associated with this outcome. ERAT may provide sustained symptom relief while preserving the appendix, although prospective multicenter controlled studies are needed.
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