Evidence map›Paper›PMID 42835054›Full record

ArticleFrontiers in cardiovascular medicine2026

The association between body composition and arterial stiffness: investigating the influence of inflammatory markers.

Julia Neubauer, Dennis Freuer, Marlene Haupt, Jakob Linseisen, Christine Meisinger, Simone Fischer

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Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Julia NeubauerFaculty of Social Work, Health & Nursing, University of Applied Sciences Ravensburg-Weingarten, Weingarten, Germany.
Dennis FreuerEpidemiology, Medical Faculty, University of Augsburg, Augsburg, Germany.
Marlene HauptFaculty of Social Work, Health & Nursing, University of Applied Sciences Ravensburg-Weingarten, Weingarten, Germany.
Jakob LinseisenEpidemiology, Medical Faculty, University of Augsburg, Augsburg, Germany.
Christine MeisingerEpidemiology, Medical Faculty, University of Augsburg, Augsburg, Germany.
Simone FischerEpidemiology, Medical Faculty, University of Augsburg, Augsburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Body fat distribution may influence arterial stiffness through inflammatory pathways, but evidence from relatively healthy adults and across complementary measures of arterial stiffness remains limited. This study investigated associations between bioelectrical impedance-derived body composition measures and arterial stiffness and assessed whether selected markers of inflammation and endothelial activation explained these associations. Methods: This study utilized cross-sectional baseline data from the MEGA study, involving 219 healthy non-obese (BMI < 30 kg/m Results: Visceral fat, total body fat, and fat mass index were positively associated with AIx: The adjusted regression coefficients were Conclusion: Higher visceral fat, total body fat, and fat mass index were associated with higher AIx, but the selected inflammatory markers did not explain these cross-sectional associations. Longitudinal studies with broader biomarker panels are needed before causal or clinical conclusions can be drawn.

Indexed as

arterial stiffnessaugmentation indexbioimpedance analysisinflammatory markersmediation analysisobesitypulse wave velocity

Identifiers

PMID42835054
PMCPMC13634821

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.