SynthesisFrontiers in physiology2026
Post-exposure effects of simulator sickness in motion-based flight simulators: a review of symptom duration and implications for flight fitness.
Synthesis in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The increasing use of modern motion-based flight simulators in military and civil aviation, despite their high relevance for training, is accompanied by the occurrence of simulator sickness. While acute symptoms during simulation are well described, the duration of post-exposure complaints and their significance for subsequent real flight capability have not yet been sufficiently investigated. The aim of this exploratory review was to summarise the available studies on the (persistence of) symptoms after flight-related simulator training. Methods: A systematic literature search was conducted in PubMed, Web of Science and Scopus in accordance with PRISMA guidelines. From a total of 4,404 hits, 14 full texts were included in this review. Results: The studies showed considerable heterogeneity in terms of participants, simulator types, exposure duration and measuring instruments. Typical symptoms included eye strain, nausea, disorientation and, less frequently, dizziness and fatigue. Only a few studies systematically investigated after-effects beyond the immediate period following the simulation. The limited available data suggest that most complaints subside significantly within four to six hours, although individual cognitive and postural impairments may persist for longer. It is currently not possible to make reliable statements about the objective restoration of flight fitness or an evidence-based minimum waiting period between simulator training and actual flight. Discussion: Overall, there is a considerable need for research, particularly using modern full-motion simulators and standardised objective performance parameters, for deriving valid safety-related recommendations and examining symptom decay. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/, identifier CRD420251161357.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.