ArticleOphthalmology science2026
Visual Impairment and Blindness in Indian Myopes Aged 10-40 Years: A Multicenter Hospital-Based Study.
Article in Ophthalmology science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: The objective of this study was to investigate the proportion of individuals with visual impairment (VI) and blindness due to myopia based on age, gender, magnitude of myopia, and myopia-related retinal changes using a large-scale database from two large tertiary-level eye care networks in India. Design: Retrospective study. Participants: A total of 46 162 individuals with myopia (≤ -0.50) aged >10 to <40 years were included. Methods: The electronic medical record data of myopic individuals who visited two tertiary eye care centers in India between January 2018 and December 2018 were analyzed. They underwent a comprehensive ophthalmic examination, which included measuring best-corrected visual acuity (BCVA) by subjective refraction and evaluating the fundus using dilated indirect ophthalmoscopy. Visual impairment and blindness were defined using BCVA of the better-seeing eye according to the World Health Organization (WHO) criteria (VI: <20/40 to ≥20/400; blindness: <20/400). Additional analysis was performed based on the worse-seeing eye. An odds ratio was used to test the association of age, gender, and degree of myopia with VI. Main Outcome Measures: Proportion of individuals with VI and blindness among Indian individuals with myopia, stratified by degree of myopia and the presence or absence of myopia-related retinal changes. Results: Based on WHO criteria using BCVA in the better-seeing eye, the proportion of VI and blindness among individuals with myopia was 1.03% (95% confidence interval [CI], 0.93-1.12) and 0.02% (95% CI, 0.00-0.03), respectively. When defined using the worse-seeing eye, the corresponding proportions were 3.53% for VI and 0.38% for blindness. The proportion of VI increased with the severity of myopia, rising from 0.14% in mild myopia to 11.96% in very high myopia, and was higher in the presence of myopia-related retinal lesions (0.41% vs. 7.62%). Conclusions: In this large hospital-based cohort, VI was present in about 1% of young and middle-aged individuals (10 to 39.9 years) with myopia and in 4% of those with high myopia. The occurrence of VI was 15 times higher in individuals with myopia-related retinal lesions than in those without retinal changes. Financial Disclosures: The authors have no proprietary or commercial interest in any materials discussed in this article.
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