Evidence map›Paper›PMID 42834751›Full record

ArticleAnnals of medicine2026

Patient-Reported Outcome scale for Bronchiectasis (BE-PRO): development and validation in China.

Yang Xie, Peng Zhang, Jiajia Wang, Tao Chen, Jiansheng Li

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yang XieDepartment of Respiratory Diseases, National Medical Center, The First Affiliated Hospital, Henan University of Chinese Medicine, Zhengzhou, China.
Peng ZhangDepartment of Respiratory Diseases, National Medical Center, The First Affiliated Hospital, Henan University of Chinese Medicine, Zhengzhou, China.
Jiajia WangDepartment of Respiratory Diseases, National Medical Center, The First Affiliated Hospital, Henan University of Chinese Medicine, Zhengzhou, China.
Tao ChenHenan International Joint Laboratory of Evidence-Based Evaluation for Respiratory Diseases, The First Affiliated Hospital, Henan University of Chinese Medicine, Zhengzhou, China.
Jiansheng LiDepartment of Respiratory Diseases, National Medical Center, The First Affiliated Hospital, Henan University of Chinese Medicine, Zhengzhou, China.ORCID 0000-0002-6485-2371

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatient-reported outcomes (PROs) have become essential endpoints in clinical trials for bronchiectasis. However, no validated PRO instrument currently exists for the Chinese population. This study aimed to develop and validate a disease-specific Patient-Reported Outcome scale for Bronchiectasis (BE-PRO) tailored to Chinese patients.

methodsA mixed-methods approach was used to develop the BE-PRO. The conceptual framework and initial item pool were developed primarily from semi-structured patient interviews and supplemented by literature and existing-instrument reviews and medical-record analysis. Items were refined through qualitative review by experts and patients. Two field surveys were then conducted, with items selected using classical test theory (CTT), item response theory (IRT), and structural equation modeling (SEM). Finally, a formal validation survey assessed the psychometric properties of the BE-PRO.

resultsThe final BE-PRO consists of 16 items organized into five domains: physiology, psychology, environment, society, and treatment satisfaction. The scale demonstrated excellent internal consistency (Cronbach's

conclusionThe 16-item BE-PRO is a reliable, psychometrically validated and feasible instrument for assessing patient-reported outcomes in Chinese patients with bronchiectasis. Its strong psychometric properties support its use in both clinical trials and routine practice.

Indexed as

BronchiectasisPatient Reported Outcome MeasuresAdultAgedChinaFemaleHumansMaleMiddle AgedPatient SatisfactionPsychometricsQuality of LifeReproducibility of ResultsSurveys and QuestionnairesBronchiectasispatient-reported outcome measurequality of life

Identifiers

PMID42834751
PMCPMC13644423

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