ArticleTrends in neurosciences2026
A microglial circadian clock sculpts synapses during neurodevelopment.
Article in Trends in neurosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
In a recent study, Routh and colleagues demonstrated that the circadian clock regulates microglia-directed synaptic refinement during a critical period of neurodevelopment in mice, in a sex-dependent manner. Loss of the major circadian rhythm regulator, Bmal1, in microglia induced a proinflammatory state and excessive pruning of synapses, primarily in adolescent male mice.
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