Evidence map›Paper›PMID 42832565›Full record

ArticleeLife2026

Human CD1c-autoreactive T-cells recognise

Matthew Milton, Sahar H Farag, Diana Garay-Baquero, Jennie Gullick, Kinga Niedobecka, Daniel Burns, Rita Szoke-Kovacs, Patrick Trimby-Smith, Alex Look, Richard Stopforth and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Matthew Milton *School of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.ORCID https://orcid.org/0000-0003-2509-7171
Sahar H Farag *School of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Diana Garay-BaqueroSchool of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.ORCID https://orcid.org/0000-0002-9450-8504
Jennie GullickSchool of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Kinga NiedobeckaSchool of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Daniel BurnsSchool of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Rita Szoke-KovacsImmunocore Limited, Abingdon, United Kingdom.
Patrick Trimby-SmithSchool of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Alex LookSchool of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.ORCID https://orcid.org/0000-0002-8492-0888
Richard StopforthSchool of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Marco LeporeImmunocore Limited, Abingdon, United Kingdom.
David K ColeImmunocore Limited, Abingdon, United Kingdom.
Laura DenneySchool of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Andrew WhiteResearch and Evaluation, UK Health Security Agency, Porton Down, United Kingdom.ORCID https://orcid.org/0000-0001-9481-0079
Sally SharpeResearch and Evaluation, UK Health Security Agency, Porton Down, United Kingdom.
Alasdair LeslieAfrica Health Research Institute, Durban, South Africa.
Andres VallejoSchool of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Liku TezeraSchool of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.ORCID https://orcid.org/0000-0002-7898-6709
Paul ElkingtonSchool of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.ORCID https://orcid.org/0000-0003-0390-0613
Salah MansourSchool of Clinical and Experimental Sciences, NIHR Southampton Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.ORCID https://orcid.org/0000-0002-5982-734X

Funding

Cancer Research UK 23562Gates Foundation OPP1137006Medical Research Council MR/P023754/1Medical Research Council MR/S024220/1Medical Research Council MR/W007045/1Medical Research Council MR/W025728/1Wellcome TrustWellcome Trust 10.35802/210662
6 · The paper itself

Abstract

Tuberculosis (TB), caused by

Indexed as

Antigen-Presenting CellsAntigens, CD1Mycobacterium tuberculosisT-LymphocytesTuberculosisGlycoproteinsHumansAntigens, CD1CD1C protein, humanGlycoproteinsautoreactive T-cellsCD1ccytotoxic T-cellshumanimmunologyinfectious diseaseinflammationlipid antigen presentationmicrobiologyMycobacterium tuberculosistuberculosis

Identifiers

PMID42832565
PMCPMC13638199

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.