Evidence map›Paper›PMID 42832099›Full record

ArticleLung2026

Clinical Characteristics and Outcomes of Patients with Lymphangioleiomyomatosis.

Hee-Young Yoon, Sung Woo Park, Jong Sun Park, Byoung Soo Kwon, Yong Suk Jo, Yangjin Jegal, Ju Hyun Oh, Joo Hun Park, Jae Ha Lee, Hongseok Yoo and 5 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Lung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hee-Young YoonDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea.
Sung Woo ParkDivision of Allergy and Respiratory Medicine, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Republic of Korea.
Jong Sun ParkDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.
Byoung Soo KwonDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.
Yong Suk JoDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Yangjin JegalDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea.
Ju Hyun OhDepartment of Pulmonology and Critical Care Medicine, Ajou University School of Medicine, Suwon, Republic of Korea.
Joo Hun ParkDepartment of Pulmonology and Critical Care Medicine, Ajou University School of Medicine, Suwon, Republic of Korea.
Jae Ha LeeDivision of Pulmonology, Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.
Hongseok YooDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Bo-Guen KimDivision of Pulmonary Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Tae Hun KimDivision of Pulmonary Medicine, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, Republic of Korea.
Jin Kyung ParkDepartment of Pulmonary, Allergy and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, School of Medicine, Kyung Hee University, Seoul, Republic Of Korea.
Ala WooDivision of Pulmonology, Department of Internal Medicine, Institute of Chest Diseases, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jin Woo SongDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 05505, Republic of Korea. jwsongasan@gmail.com.ORCID http://orcid.org/0000-0001-5121-3522

Funding

Korea Ministry of Environment 2024ER090500National Research Foundation of Korea NRF-2022M3A9E4082647RS-2022-KE002197 Korea Ministry of Environmentthe Korean Academy of Tuberculosis and Respiratory Diseases KATRD-S-2022-1
6 · The paper itself

Abstract

backgroundLymphangioleiomyomatosis (LAM) is a rare, progressive cystic lung disease that affects women of reproductive age. Although registries from Western countries have provided key insights, comprehensive nationwide data from Asian countries are scarce. This study aimed to characterise the clinical, functional and outcome features of Korean patients with LAM from a nationwide multicentre registry.

methodsWe analyzed data from patients with LAM enrolled in the Korean Nationwide Rare Interstitial Lung Disease Registry in 2024. Data on clinical and functional characteristics were collected from 20 centers. Longitudinal changes in pulmonary function were assessed using linear mixed-effects models. Individual annual forced expiratory volume in 1 s (FEV

resultsEighty-six women (mean age, 47.3 years) were included; 50% were asymptomatic at diagnosis and 61.6% had complications, including pneumothorax (29.1%) and renal angiomyolipoma (25.6%). Baseline mean forced vital capacity (FVC) and FEV

conclusionThis study provides a nationwide characterization of LAM in Korea, showing preserved lung function at diagnosis and frequent mTOR inhibitor use.

Indexed as

LungLung NeoplasmsLymphangioleiomyomatosisAdultCoughDisease ProgressionFemaleForced Expiratory VolumeHumansMiddle AgedMTOR InhibitorsPneumothoraxPulmonary Diffusing CapacityRegistriesRepublic of KoreaRespiratory Function TestsMTOR InhibitorsLymphangioleiomyomatosisMulticenter studiesPulmonary function testsRare diseasesRegistries

Identifiers

PMID42832099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.